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Asst Prof Unadkat Hemant Vijaykumar

BDS, MSc (Newcastle upon Tyne), PhD (the Netherlands)

Clinician Scientist

National Dental Centre Singapore

Profile

Dr. Hemant Unadkat is an Assistant Professor at Duke-NUS Medical School, Clinician Scientist, Principal Investigator at the National Dental Centre Singapore. His innovative lab focuses on using biomaterials engineering and micro- and nanotechnologies to improve oral health through craniofacial tissue regeneration and disease modelling.

His research programme merges discovery and application, incorporating high-throughput technologies, cell biology, and artificial intelligence for practical clinical use. Dr. Unadkat's long-term goal is to make a lasting impact on craniofacial tissue engineering.

His work has been published in reputable journals, such as PNAS, and highlighted in Nature, Nature Materials, and Nature Methods. With over S$6 Million in research funding and numerous patent applications, Dr. Unadkat demonstrates dedication to advancing his field. He is only the second dentist in Singapore to receive the prestigious Ministry of Health and National Medical Research Council Transition Award. Recently, he has also received the NMRC Clinician Scientist Individual Research Grant.

Education

Bachelor of Dental Surgery (BDS), Nagpur University, India (2002)
Master of Science, Biomedical Nanotechnology (MSc), University of Newcastle upon Tyne, UK (2005)
Doctor of Philosophy, Biomaterials and Tissue Regeneration (PhD), University of Twente. Enschede, The Netherlands (2012)

Professional Appointments and Committee Memberships

Board Member, Research Advisory and Monitoring Board, Datta Meghe Institute of Medical Sciences (Deemed University), India
Board Member, SingHealth Intellectual Property evaluation committee, SingHealth Intellectual Property Office (SHIP)
Board Member, National Dental Centre new building planning committee
Board Member, National Dental Centre Research Review Committee

Awards

Ministry of Health and National Medical Research Council Singapore, Transition Award Aug 2016
European society for biomaterials and tissue engineering doctoral award 2013
MBI Postdoctoral Research Fellowship 2012
BD Biosciences award for significant contribution to the development of high content imaging 2010
InventScience travel award by 4th Marie Curie Cutting-Edge Conference 2007
National Merit Scholarship: Government of India 1997 and 1995.

Research Interests

Stem Cell material interactions, mechanotransduction
Developmental bioengineering for craniofacial regeneration
Materiomics: high content and high throughput screening of biomaterials
Lab on a chip based applications

Publications

Unadkat, H. V.; Groen, N.; Doorn, J.; Fischer, B.; Barradas, A. M. C.; Hulsman, M.; van de Peppel, J.; Moroni, L.; van Leeuwen, J. P.; Reinders, M. J. T.; van Blitterswijk, C. A.; de Boer, J. High content imaging in the screening of biomaterial-induced MSC behavior Biomaterials 34 (5), 1498-1505 (2013)
Unadkat, H. V.; Hulsman, M.; Cornelissen, K.; Papenburg, B. J.; Truckenmüller, R. K.; Carpenter, A. E.; Wessling, M.; Post, G. F.; Uetz, M.; Reinders, M. J. T.; Stamatialis, D.; van Blitterswijk, C. A.; de Boer, J. An algorithm-based topographical biomaterials library to instruct cell fate Proceedings of the National Academy of Sciences 108, 16565-16570 (2011) Research Highlight: Nature 478, 9; 2011, Nature Methods 8, 900; (2011), Nature Materials 10, 808; (2011), Neurosurgery; 70, 2; (2012), Biomaterials Forum, 33, 4 (2011)
Truckenmüller, R. K.; Giselbrecht, S.; Escalante-Marun, M.; Groenendijk, M.; Papenburg, B.; Rivron, N.; Unadkat, H.; Saile, V.; Subramaniam, V.; van den Berg, A.; van Blitterswijk, C. A.; Wessling, M.; de Boer, J.; Stamatialis, D.; Fabrication of cell container arrays with overlaid surface topographies. Biomedical Microdevices, 1-13
Hulsman, M.; Hulshof, G. F. B.; Unadkat, H. V.; Papenburg, B. J.; Truckenmüller, R.; Stamatialis, D. F.; van Blitterswijk, C. A.; de Boer, J.; Reinders, M. J. T. Analysis of high-throughput screening reveals the effect of surface topographies on cellular morphology Acta Biomaterialia 15, 29–38 (2015)
Unadkat, H. V.; Rewagad, R.; Hulsman, M.; Hulshof, G. F. B.; Truckenmüller, R.; Stamatialis, D. F.; Reinders, M. J. T.; Eijkel, J. C. T.; van den Berg, A.; van Blitterswijk, C. A.; de Boer, J. A modular versatile chip carrier for high throughput screening of cell-biomaterial interactions J. R. Soc. Interface 10 (78), 1742-5662 (2013) Research Highlight: Lab on Chip, 13, 1453-1456, 2013
Anand, R.; Sarode G.S.; Sarode, S.C.; Unadkat, H.; Mushtaq, S.; Deshmukh, R.; Chaudhary, S. Clinico-pathological characteristics of desmoplastic ameloblastoma: a systematic review. J Oral Pathol Med 2017
Sarode, S.C.; Sarode, G.S.; Anand, R.; Patil S.; Unadkat H. WhatsApp is an effective tool for obtaining second opinion in oral pathology practice. J Oral Pathol Med (2016) Oct 22.
Bettahalli, N. M. S.; Groen, N.; Steg, H.; Unadkat, H.; de Boer, J.; van Blitterswijk, C. A.; Wessling, M.; Stamatialis. D.; Development of Multilayer Constructs for Tissue Engineering Journal of Tissue Engineering and Regenerative Medicine (2012) doi: 10.1002/term.1504
Stamatialis, D. F.; Bettahalli, N. M. S.; Vicente, J.; Moroni, L.; Higuera, G. A.; Groen, N.; Stag, H.; Unadkat, H.; de Boer, J.; van Blitterswijk, C. A.; and Wessling. M. Integration of Hollow Fiber Membranes Improves Nutrient Supply in 3d Tissue Constructs International Journal of Artificial Organs 34, no. 8 (2011): 645-645.
van Blitterswijk, C. A.; Stamatialis, D.; Unadkat, H.; Papenburg, B.; Rouwkema, J.; Truckenmuller, R.; van Apeldoorn, A.; Wessling, M.; and de Boer, J. Materiomics: Dealing with Complexity in Tissue Engineering European Cells and Materials 20, no. 1: 1. (2010)
Unadkat, H.V.; Hulsman, M.; Cornelissen, K.; Papenburg, B.; Truckenmüller, R. K.; Post, G. F.; Uetz, M.; Reinders, M.J.T.; Stamatialis, D.; van Blitterswijk, C.; De Boer, J. High-Throughput Screening of Cell-Surface Topographic Interactions 2009 IEEE NEBEC, pp.1-2, 3-5 (2009)
Cornelissen, K.; Unadkat, H. V.; Truckenmüller, R. K.; van Blitterswijk, C. A.; Post, G. F.; de Boer, J. and Uetz, M. Algorithmic Feature Generation for Microscale Topographies Proceedings of the 4th Annual symposium of the IEEE-EMBS Benelux Chapter The Netherlands, (pp. 55-55). Piscataway: IEEE.
Unadkat, H. V.; Papenburg, B. J.; Stamatialis, D.; Wessling, M.; van Blitterswijk, C. A.; and de Boer J.; High-Throughput Biological Screening of Cell-Surface Topography Interactions Tissue Engineering Part A 14, no. 5 (2008): 858-858.